Salt sensitive: Participants with SBP being at least 5 mmHg higher after HS intake compared to the values after the LS intake; Salt resistant: Participants whose SBP differed by <5 mmHg between HS and LS intakes; Independent variables: Urinary Na + , Urinary K + and Na + :K + excretion ratio; Dependent variable: SBP; Categorical variable: Participants were categorized into groups on the basis of increments of 1 g/day in urinary Na + and K + excretion to evaluate the linear trends
Analytical study
General linear patterns was used for linear regression data (Pearson’s Roentgen correlation) to evaluate the fresh relationship from urinary Na + and you can K + removal having SBP. To own Figs. 2 and you may step three, two-means ANOVA having Tukey’s article hoc was did to compare SBP one of several communities outlined on the basis of urinary Na + and K + excretion. So you’re able to quantify the effectiveness of increasing urinary Na + and you will K + removal according to SBP, Cohn’s Feeling Dimensions is actually calculated. In the Figs. cuatro and you can 5 generalized Pearson’s R relationship try performed to evaluate the latest organization of one’s urinary Na + :K + removal proportion having SBP. Within the Fig. 6 analysis was indeed reviewed of the a good three-method ANOVA together with pairwise comparisons have been made having fun with Tukey’s post hoc try. During the Fig. eight cousin regularity distribution try assessed playing with a good Gaussian fit studies. 05 (GraphPad prism app, adaptation 8). Data is actually displayed while the imply ± SD.
Baseline systolic blood pressure (SBP) at screening 
on regular diet (a) according to changes potassium excretion for salt sensitive (n = 186) and salt resistant (n = 222) group, slope for salt sensitive and salt resistant group is indicated for the potassium excretion range <1–1
Baseline systolic blood pressure (SBP) at screening on regular diet (a) according to changes sodium excretion of <5 g/day, in salt sensitive (n = 154) and salt resistant (n = 180) group, slope of the for salt sensitive group is indicated for the sodium excretion ranges of <2–2.99 g/day, 3–3.99 g/day and 4–4.99 g/day (b) Correlation of baseline SBP (dependent variable) across the entire range of urinary sodium excretion (independent variable), (Pearson's R 2 for salt sensitive = 0.02 and for salt resistant = 0.02), in salt sensitive (n = 186) and salt resistant (n = 222) individuals.
99 g/go out, thinking revealed as imply ± SD. b Correlation out-of standard SBP (dependent variable) across the whole assortment urinary potassium removal (independent variable), (Pearson’s Roentgen dos for salt sensitive and painful = 0.001 and you can salt resistant = 0.008), in sodium sensitive and painful (letter = 186) and you can sodium resistant (letter = 222) anybody.
Baseline SBP according to urinary sodium so you’re able to potassium excretion ratio (Na + /K + ) (a) correlation off standard SBP (situated adjustable) over the entire selection of urinary Na + /K + excretion (separate adjustable), (Pearson’s Roentgen 2 getting salt painful and sensitive = 0.0004 and you can salt resistant = 0.0016) (b) baseline SBP predicated on alterations in salt excretion and you may potassium excretion variety from inside the sodium delicate (letter = 186) and you can salt resistant (n = 222) individuals at assessment on the typical eating plan, beliefs revealed as the suggest ± SD. Studies had been analyzed because of the about three-means ANOVA which have pairwise analysis followed by Tukey’s article hoc sample.
Relationship of SBP viewpoints over the whole list of urinary sodium so you can potassium excretion (Na + /K + ) proportion inside salt painful and sensitive (letter = 71) and you will sodium resistant (letter = 119) those with diet intervention of your Weight loss Remedies for End Hypertension (DASH) (a) higher sodium (HS), (Pearson’s Roentgen dos for salt sensitive = 0.04 and you may salt unwilling = 0.04) (b) reduced sodium (LS) diet plan, (Pearson’s Roentgen dos for sodium painful and sensitive = 0.02 and you will sodium unwilling = 0.00002).